Intranet PAC-CI
Published on 07 Apr 2026

PAC-CI and the COTRIMO-CI trial: the first steps in a commitment to patient care

Christian KOUADIO

Researcher, PAC-CI

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PAC-CI and the COTRIMO-CI trial: the first steps in a commitment to patient care

Summary & Key Points

"Did you know? PAC-CI has been committed early on to the fight against opportunistic infections. From its inception, the PAC-CI Programme has addressed a major public health challenge: combating opportunistic infections in people living with HIV."

Did you know?

PAC-CI has been committed early on to combating opportunistic infections

From its inception, the PAC-CI Program tackled a major public health challenge: fighting opportunistic infections in people living with HIV.

Opportunistic infections are diseases that occur more easily when the immune system is weakened. In the case of HIV, they posed a particularly serious threat to patients in the 1990s, especially in a context where antiretroviral treatments were still largely inaccessible in sub-Saharan Africa.

Faced with this situation, a key question arose: how could people living with HIV be better protected against these serious diseases, at a time when therapeutic options remained limited?

It was in this context that PAC-CI conducted a major trial in Côte d’Ivoire: the COTRIMO CI trial. This study is among the first major research projects that helped build the Program’s reputation in the health field.

Through this trial, PAC-CI contributed to finding concrete solutions to improve care for the most vulnerable patients.

In our next article, discover what the COTRIMO trial demonstrated and how its results marked a turning point in the prevention of opportunistic infections.

Christian KOUADIO

Clinical Research Associate and Communications Manager at PAC-CI

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